Abstract:
Introduction: Although diabetes is a multi-systemic disorder its pulmonary involvement is not extensively
studied. Pathoanatomical studies in diabetic patients have represented changes in basal lamina of alveolar epithelium and capillaries. This study was undertaken to find out the correlation between duration of DM and PFTs in patients who attended or admitted to medical OPD of Ziaur Rahman Medical College Hospital, Bogura, Bangladesh.
Aims and Objectives: The present study is conducted to find the relation between duration of diabetes and its
impairment of pulmonary function tests (PFT) in Type 2 DM patients.
Study Population: One hundred diabetic patients previously diagnosed, belonging to either sex attending admitting to OPD of Ziaur Rahman Medical College Hospital, Bogura, Bangladesh during from March to August 2019.
Methods: Patients will be classified into three groups A, B, C depending on the duration of diabetes. Group A
consists of diabetes with duration of up to 3 years. Group B consists of diabetes with duration of 3to 5 years. Group C consists of diabetes with duration more than 5 years. Pulmonary function tests were done for all cases and controls.
Results: Our results showed that diabetic patients have reduced FEV1, FVC, FEV1/FVC%, PEFR when
compared with healthy non diabetic controls. Mean FEV1 in our study is 2.496 litres/min which is reduced significantly than control (p<0.001).Mean FVC in our study is 3.161 which is reduced significantly (p<0.001).There is a restrictive pattern in diabetics when compared with the non-diabetic controls of same age.
Conclusion: Type-2 diabetic patients have reduced FEV1, FVC, PEFR when compared with non-diabetics of
same age. Type 2 diabetic patients have a restrictive pattern of pulmonary function tests even in the absence of any symptoms. This restrictive pattern is more prominent as the duration of diabetes is increased. Periodic monitoring of lung functions is necessary in diabetics as spirometry is a cost effective, non-invasive tool.
